Glycerin 3 Phosphat Shuttle. Glycerol 3 Phosphate Shuttle Another Ca 2+-sensitive booster of mitochondrial ATP synthesis is the glycerol-3-phosphate shuttle (G3PS), whose role in neuronal energy supply has remained elusive Essential components of G3PS are expressed in hippocampal neurons
Identification of a mammalian glycerol3phosphate phosphatase Role in metabolism and signaling from www.pnas.org
The shuttle also operates in yeast, animals and plants [PMID: 16415206][9171333][9559543] The yield is lower because FAD rather than NAD + is the electron acceptor in mitochondrial glycerol 3-phosphate dehydrogenase.
Identification of a mammalian glycerol3phosphate phosphatase Role in metabolism and signaling
In G3PS, NAD + is regenerated by cytosolic glycerol-3-phosphate dehydrogenase (GPD) by converting dihydroxyacetone phosphate (DHAP) into glycerol-3-phosphate (G3P) NADH must be transported into the mitochondria to enter the oxidative phosphorylation pathway. The glycerol-3-phosphate shuttle is a biochemical pathway that facilitates the transport of electrons from cytosolic NADH into the mitochondria, allowing for ATP production during cellular respiration
Glycerol3Phosphate Shuttle Mitochondrial Respiration Biochemistry Basics YouTube. The shuttle also operates in yeast, animals and plants [PMID: 16415206][9171333][9559543] The glycerol-3-phosphate (G-3-P) shuttle is an important pathway for delivery of cytosolic reducing equivalents into mitochondrial oxidative phosphorylation, and plays essential physiological roles in yeast, plants, and animals
Mitochondrial shuttles. (A) The glycerol3phosphate shuttle. cGPD =... Download Scientific. Single neuron metabolic measurements in primary hippocampal cultures derived from rat pups of either sex reveal. The yield is lower because FAD rather than NAD + is the electron acceptor in mitochondrial glycerol 3-phosphate dehydrogenase.